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Microbiome Updates & Sharing-Protocol for oral fecal gavage to reshape the gut microbiota in mice
Summary
Fecal microbiota transplantation (FMT) is clinically applied, while oral FMT (oral fecal gavage [OFG]) is preferred for experimental mice. Here, we present a protocol for OFG in antibiotic-pretreated mice, demonstrating the progressive, time-dependent evolution of the gut microbiota in the recipients. We describe steps for fecal sample collection and preparation procedures, oral gavage, and monitoring gut microbiota changes. This protocol serves as a general guide for reshaping the gut microbiota in recipient mice for various experimental applications.
Read the full article here: Protocol for oral fecal gavage to reshape the gut microbiota in mice
